The Effect of Reiki on Anxiety, Stress, and Comfort Levels Before Gastrointestinal Endoscopy: A Randomized Sham-Controlled Trial

Published:October 20, 2022DOI:



      This study's aim is to determine the effect of Reiki when applied before upper gastrointestinal endoscopy on levels of anxiety, stress, and comfort.


      This single-blind, a pretest and post-test design, randomized, sham-controlled study was held between February and July 2021.


      Patients who met the inclusion criteria were separated by randomization into three groups: Reiki, sham Reiki, and control. A total of 159 patients participated in the study. In the intervention groups (Reiki and sham Reiki), Reiki and sham Reiki were applied once for approximately 20 to 25 minutes before gastrointestinal endoscopy.


      When the Reiki group was compared to the sham Reiki and control groups following the intervention, the decrease in the levels of patient stress (P < .001) and anxiety (P < .001) and the increase in patient comfort (P < .001) were found to be statistically significant.


      Reiki applied to patients before upper gastrointestinal endoscopy was effective in reducing stress and anxiety and in increasing comfort.


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        • Ceyhan O
        • Tekinsoy Kartin P
        • Tasci S.
        Effect of anxiety evel of education in patients of endoscopy.
        Pamukkale Med J. 2018; 11: 293-300
        • Shaermoghadam S
        • Shahdadi H
        • Khorsandvakilzadeh A
        • Afshari M
        • Badakhsh M.
        Comparison of the effects of foot and hand reflexology massages on stress and anxiety in candidate patients undergoing upper gastrointestinal endoscopy.
        IJPCR. 2016; 8: 1254-1259
        • Sogabe M
        • Okahisa T
        • Adachi Y
        • et al.
        The influence of various distractions prior to upper gastrointestinal endoscopy: a prospective randomized controlled study.
        BMC Gastroenterol. 2018; 18: 132
        • Armellini E
        • Repici A
        • Alvisi C
        • et al.
        Analysis of patients attitude to undergo urgent endoscopic procedures during COVID-19 outbreak in Italy.
        Dig liver Dis. 2020; 52: 695-699
        • Hulse RS
        • Stuart-Shor EM
        • Russo J.
        Endoscopic procedure with a modified Reiki intervention: a pilot study.
        Gastroenterol Nurs. 2010; 33: 20-26
        • Kilicarslan N
        • Gurbuz H
        • Balkaya AN
        • Karasu D
        • Demiroren K
        • Gamli M.
        Procedural sedation practices during percutaneous endoscopic gastrostomy in patients with cerebral palsy.
        Black Sea J Heal Sci. 2021; (doi:10.19127/bshealthscience.1009012. (in Turkish)): 65-70
        • Amornyotin S.
        Sedation-related complications in gastrointestinal endoscopy.
        World J Gastrointest Endosc. 2013; 5: 527
        • Topdemir EA
        • Saritas S.
        The effect of preoperative Reiki application on patient anxiety levels.
        Explore (NY). 2021; 17: 50-54
        • Webster LC
        • Holden JM
        • Ray DC
        • Price E
        • Hastings TM.
        The impact of psychotherapeutic Reiki on anxiety.
        J Creat Ment Heal. 2020; 15: 311-326
        • Kurebayashi LFS
        • Gnatta JR
        • Kuba G
        • Giaponesi ALL
        • Souza TPB de
        • Turrini RNT.
        Massage and Reiki to reduce stress and improve quality of life: a randomized clinical trial.
        Rev Esc Enferm USP. 2020; 54: 1-7
        • Bat N.
        The effects of Reiki on heart rate, blood pressure, body temperature, and stress levels: a pilot randomized, double-blinded, and placebo-controlled study.
        Complement Ther Clin Pract. 2021; 43101328
        • Dyer NL
        • Baldwin AL
        • Rand WL.
        A large-scale effectiveness trial of Reiki for physical and psychological health.
        J Altern Complement Med. 2019; 25: 1156-1162
        • Zins S
        • Hooke MC
        • Gross CR.
        Reiki for pain during hemodialysis: a feasibility and ınstrument evaluation study.
        J Holist Nurs. 2019; 37: 148-162
        • Bremner MN
        • Blake BJ
        • Wagner VD
        • Pearcey SM.
        Effects of Reiki with music compared to music only among people living with HIV.
        J Assoc Nurses AIDS Care. 2016; 27: 635-647
        • Rao A
        • Hickman LD
        • Sibbritt D
        • Newton PJ
        • Phillips JL.
        Is energy healing an effective non-pharmacological therapy for improving symptom management of chronic illnesses? A systematic review.
        Complement Ther Clin Pract. 2016; 25: 26-41
        • Bukowski EL.
        The use of self-Reiki for stress reduction and relaxation.
        J Integr Med. 2015; 13: 336-340
        • Demir Doğan M.
        The effect of Reiki on pain: a meta-analysis.
        Complement Ther Clin Pract. 2018;
        • Monfared A
        • Mirzaee Jirdehi M
        • Mansour Ghanaei F
        • Joukar F
        • Kazemnezhad Leyli E
        The effect of lavender essential oil aromatherapy on the anxiety of endoscopy candidates: a clinical trial.
        Iran J Nurs. 2020; 32: 55-68
        • Schulman AR
        • Popov V
        • Thompson CC.
        Randomized sham-controlled trials in endoscopy: a systematic review and meta-analysis of adverse events.
        Gastrointest Endosc. 2017; 86: 972-985.e3
      1. RANDOM.ORG website. Accessed 14 February 2021.

        • Abdulraheem S
        • Bondemark L.
        Hawthorne effect reporting in orthodontic randomized controlled trials: truth or myth? Blessing or curse?.
        Eur J Orthod. 2018; 40: 475-479
        • Baldwin AL
        • Vitale A
        • Brownell E
        • Kryak E
        • Rand W.
        Effects of Reiki on pain, anxiety, and blood pressure in patients undergoing knee replacement: a pilot study.
        Holist Nurs Pract. 2017; 31: 80-89
        • DiScipio WJ.
        Perceived relaxation as a function of restorative yoga combined with Reiki for cancer survivors.
        Complement Ther Clin Pract. 2016; 24: 116-122
        • Lesage FX
        • Berjot S
        • Deschamps F.
        Clinical stress assessment using a visual analogue scale.
        Occup Med (Chic Ill). 2012; 62: 600-605
        • Spielberger CD
        • Gorsuch RL
        • Lushene RE.
        Manual for the State-Trait Anxiety Inventory. 1st. Consulting Psychologists Press, Polo Alto, CA1970
        • Oner N.
        Psychological tests used in Turkey, a reference.
        3rd. Boğaziçi University Publications, Istanbul1997 (in Turkish)
        • Kolcaba K
        • Tilton C
        • Drouin C.
        Comfort theory: A unifying framework to enhance the practice environment.
        J Nurs Adm. 2006; 36: 538-544
        • Citlik Saritas S
        • Cevik S
        • Ozden G.
        Validity and reliability study of the turkish version of the short general comfort questionnaire.
        J  Nurs Forum Diabetes Obes Hypertension. 2018; 10 (in Turkish): 16-22
        • Citlik Saritas S
        • Cevik S
        • Ozden G
        Validity and reliability study of the turkish version of the short general comfort questionnaire.
        J Nurs Forum Diabetes Obesity Hypertension. 2018; 10 (in Turkish): 16-22
        • Muller B
        • Gunther HH.
        Reiki applied healing techniques.
        in: Oner G What is reiki? Remzi Bookstore, Istanbul2012 (:22. (in Turkish))
        • Buyukbayram Z
        • Citlik Saritas S
        The effect of Reiki and guided imagery intervention on pain and fatigue in oncology patients: a non-randomized controlled study.
        Explore (NY). 2021; 17: 22-26
        • Díaz-Rodríguez L
        • Arroyo-Morales M
        • Fernández-de-las-Peñas C
        • García-Lafuente F
        • García-Royo C
        • Tomás-Rojas I.
        Immediate effects of Reiki on heart rate variability, cortisol levels, and body temperature in health care professionals with burnout.
        Biol Res Nurs. 2011; 13: 376-382
        • Rosada RM
        • Rubik B
        • Mainguy B
        • Plummer J
        • Mehl-Madrona L.
        Reiki reduces burnout among community mental health clinicians.
        J Altern Complement Med. 2015;
        • Salles LF
        • Vannucci L
        • Salles A
        • Silva MJP.
        The effect of Reiki on blood hypertension.
        Acta Paulista de Enfermagem. 2014; 27: 479-484
        • Bondi A
        • Morgan T
        • Fowler SB.
        Effects of Reiki on pain and anxiety in women hospitalized for obstetrical- and gynecological-related conditions.
        J Holist Nurs. 2020; 39: 58-65
        • Bukowski EL
        • Berardi D.
        Reiki brief report: using Reiki to reduce stress levels in a nine-year-old child.
        Explore (NY). 2014; 10: 253-255
        • Thrane S
        • Cohen SM.
        Effect of Reiki therapy on pain and anxiety in adults: an in-depth literature review of randomized trials with effect size calculations.
        Pain Manag Nurs. 2014; 15: 897-908
        • Rosenbaum MS
        • Velde J.
        The Effects of yoga, massage, and Reiki on patient well-being at a cancer resource center.
        Clin J Oncol Nurs. 2016; 20: E77-E81
        • Birocco N
        • Guillame C
        • Storto S
        • et al.
        The effects of Reiki therapy on pain and anxiety in patients attending a day oncology and infusion services unit.
        Am J Hosp Palliat Care. 2012; 29: 290-294
        • Demir M
        • Can G
        • Kelam A
        • Aydiner A.
        Effects of distant Reiki on pain, anxiety and fatigue in oncology patients in Turkey: a pilot study.
        Asian Pacific J Cancer Prev. 2015;
      2. National Center for Complementary and Integrative Health. Reiki. Accessed 5 May 2021.

        • Ivanchenko A.
        Positive impact of recreational techniques for the self-healing of the body.
        Estud Psicol. 2020; 37: 1-13
        • McManus DE.
        Reiki Is better than placebo and has broad potential as a complementary health therapy.
        J Evid Based Complementary Altern Med. 2017; 22: 1051-1057
        • Chirico A
        • D'Aiuto G
        • Penon A
        • et al.
        Self-efficacy for coping with cancer enhances the effect of Reiki treatments during the pre-surgery phase of breast cancer patients.
        Anticancer Res. 2017; 37: 3657-3665
        • Midilli TS
        • Eser I.
        Effects of Reiki on post-cesarean delivery pain, anxiety, and hemodynamic parameters: a randomized, controlled clinical trial.
        Pain Manag Nurs. 2015; 16: 388-399
        • Cassidy N
        • Collins K
        • Cyr D
        • Magni K.
        The Effect of Reiki on women's preoperative anxiety in an ambulatory surgery center.
        J Peri Anesthesia Nurs. 2010; 25: 196
      3. American Psychological Association. Anxiety. Accessed 10 May 2021.

        • Rosier PK.
        Comfort theory and practice: a vision for holistic health care and research.
        in: Kathleen W Clinical Nurse Specialist. Springer Publish Company, New York, NY2005: 49
        • Catlin A
        • Taylor-Ford RL.
        Investigation of standard care versus sham Reiki placebo versus actual Reiki therapy to enhance comfort and well-being in a chemotherapy infusion center.
        Oncol Nurs Forum. 2011; 38: E212-E220