Journal of PeriAnesthesia Nursing
Volume 24, Issue 6 , Pages 406-408 , December 2009

Surgical Antibiotic Prophylaxis—Focus on Dosing

  • Julie Golembiewski, PharmD

      Affiliations

    • Corresponding Author InformationAddress correspondence to Julie Golembiewski, Department of Anesthesiology, University of Illinois Medical Center, 1740 West Taylor Street, Suite 3200 (MC515), Chicago, IL 60612-7239

References 

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  2. Institute for Healthcare Improvement. Campaign Overview, Protecting 5 Million Lives from harm. Available at: http://www.ihi.org/IHI/Programs/Campaign/Campaign.htm?TabId=1. Accessed August 14, 2009.
  3. DiPiro JT, Vallner JJ, Bowden TA, et al. Intraoperative serum and tissue activity of cefazolin and cefoxitin. Arch Surg. 1985;120:1353–1354
  4. Classen DC, Evans RS, Pestotnik SL, et al. The timing of prophylactic administration and the risk of surgical wound infection. N Engl J Med. 1992;326:281–286
  5. Abramowicz M, ed. Treatment Guidelines from the Medical Letter: Antimicrobial prophylaxis for surgery. The Medical Letter 2004;2:27-32.
  6. Zelenitsky SA, Ariano RE, Harding GK, et al. Antibiotic pharmcodynamics in surigcal prophylaxis: An association between intraoperative antibiotic concentrations and efficacy. Antimicrob Agents Chemother. 2002;46:3026–3030
  7. Koopman E, Nix DE, Erstad BL, et al. End-of-procedure cefazolin concentrations after administration for prevention of surgical-site infection. Am J Health Syst Pharm. 2007;64:1927–1934
  8. Bratzler DW, Houck PM. Antimircrobial prophylaxis for surgery: An advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis. 2004;38:1706–1715
  9. Forse RA, Karam B, MacLean LD, et al. Antibiotic prophylaxis for surgery in morbidly obese patients. Surgery. 1989;106:750–757
  10. Olsen MA, Nepple JJ, Riew KD, et al. Risk factors for surgical site infection following orthopaedic spinal operations. J Bone Joint Surg Am. 2008;90:62–69
  11. Institute for Healthcare Improvement. Use prophylactic antibiotics appropriately. Available at: http://www.ihi.org/IHI/Topics/PatientSafety/SurgicalSiteInfections/Changes/SSI+Use+Prophylactic+Antibiotics+Appropriately.htm. Accessed August 14, 2009.
  12. Edmiston CE, Krepel C, Kelly H, et al. Perioperative antibiotic prophylaxis in the gastric bypass patient: Do we achieve therapeutic levels?. Surgery. 2004;136:738–747
  13. Auwaerter P. Johns Hospkins POC-IT Center ABX Guide, Surgical Prophylaxis. January 22, 2009. Available at: http://prod.hopkins-abxguide.org/diagnosis/surgical_infections/full_surgical_prophylaxis.html. Accessed August 14, 2009.
  14. Bauer LA, Black DJ, Lill JS. Vacomycin dosing in morbidly obese patients. Eur J Clin Pharmacol. 1998;54:621–625
  15. Bauer LA, Edwards WA, Dellinger EP, et al. Influence of weight on aminoglycoside pharmacokinetics in normal weight and morbidly obese patients. Eur J Clin Pharmacol. 1983;24:643–647

PII: S1089-9472(09)00399-2

doi: 10.1016/j.jopan.2009.10.007

Journal of PeriAnesthesia Nursing
Volume 24, Issue 6 , Pages 406-408 , December 2009

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